Losing the person you love to Anti-depressants

I lost my wife to anti-depressants, not in death but as a totally different person. We were so in love but she had many self esteem issues which depressed her. A friend suggested she try anti-depressants and I agreed maybe she needed to try them. At first (lower dosage) it was working (but now looking back even that changed her) but at the time I felt there was a balance, but her doctor upped her dosage and her personality completely changed. She became another person. She no longer wanted to be with me due to these changes and she lost the qualities that made her just a good person. She was making a great deal of irrational decisions, which caused her to lose her job. She wanted to start an open relationship, and just ended up pulling away from me. And at the time it caused me to make irrational judgments because I didn't want to lose her, but in away I already had. So due to my own ignorance of what the medication was doing, because at the time I couldn’t equate the two I lost her and we went out separate ways. After talking with a number of people they had similar experiences, some losing their spouses and some figuring it out before they lost their partners to a changed personality. I say be very concerned about Anti-depressants, and the dosages as well as the types. It can take a while to find one that can help, while still keeping the root of the person who is seeking them. Don’t lose a person you love to Anti-depressants. I am finding more studies that support that Anti-depressants can create personality changes. I hope no one else has to go through what I have. I still love my now ex, but she has moved on living as a different person and I am the one who got hurt losing the person who I felt was my soulmate.